Search All of the Math Forum:

Views expressed in these public forums are not endorsed by NCTM or The Math Forum.

Notice: We are no longer accepting new posts, but the forums will continue to be readable.

Topic: Several questions on evolution, and mutation (rate)
Replies: 52   Last Post: Sep 8, 1996 9:44 PM

 Messages: [ Previous | Next ]
 James Foster Posts: 11 Registered: 12/8/04
Re: Several questions on evolution, and mutation (rate)
Posted: Sep 6, 1996 11:36 AM

Ram Samudrala (ram@mbisgi.umd.edu) wrote:

: >For example, genes which code for one protein in hemoglobin may
: >silently duplicate, and only over much time will that duplication
: >develop some functionality.

: This is what I mean by evolution! Suppose our haemoglobin genes
: tomorrow also conferred resistance to malaria (by having a few
: mutations). Wouldn't you wonder HOW a new function arose from this
: duplication (which must've been both haemoglobin initially), and how
: long it took just to come up with it?

: >It's pointless to insist on isolating the original duplication event,
: >because it was silent.

: No, not the original duplication event, but the length of time (and
: how) it takes to come up with the new functionality (which has to
: happen BEFORE natural selection).

Ahhh...gotcha. That is indeed an interesting question. I'm not sure
what the answer is. I know that many new functions are co-opted from
similar functions (I think the classical example is some enzyme
beginning with the letter l...but can't remember right now). But that
begs the question of where the co-opted behaviors came from.

Similarly, hybridization is a good source of new behavior. But again,
you have to have the hybrids to begin with.

Still, evolution is a change in distribution of characters...you are
focusing on one particular change: from zero to non-zero distribution.
That is interesting, and important.

: >The important point is that mutation without selection is not a
: >particularly interesting concept, from an evolutionary perspective.

: We disagree there too, and there's quite a bit of research on this
: topic. Basically, the idea is, how long does it take for new function
: to evolve, from an existing gene, before naturally selection can
: operate on it. How does it evolve? Is it randomly (the current
: belief) or is there some directed process going on?

OK. You convinced me. Mutation in isolation is an interesting thing to
study.

I have seen the new evidence supporting some Lamarkian mechanism, so
your last question does merit some investigation.

Thanks for the discourse. I'm outta here.
--
James A. Foster email: foster@cs.uidaho.edu
Laboratory for Applied Logic Dept. of Computer Science
University of Idaho www: http://www.cs.uidaho.edu/~foster

-----BEGIN PGP PUBLIC KEY BLOCK-----
Version: 2.6.2
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=G/K7
-----END PGP PUBLIC KEY BLOCK-----

Date Subject Author
8/15/96 Andrew Singer
8/16/96 Lluis Ribas
8/16/96 Doug Yanega
8/17/96 Leonard Evens
8/16/96 KIRKX L AUGUSTIN
8/17/96 Leonard Evens
8/28/96 Brian Williams
8/29/96 Lauren Owens
8/18/96 Felix J. Thibault
8/20/96 Vincent R. Johns
8/23/96 Richard M Kliman
8/25/96 David Beorn
8/26/96 Vincent R. Johns
8/27/96 Steve McGrew
8/27/96 James Foster
8/29/96 David Beorn
8/30/96 James Foster
8/31/96 L.A. Moran
9/3/96 James Foster
9/4/96 L.A. Moran
9/4/96 James Foster
9/4/96 Ram Samudrala
9/4/96 James Foster
9/4/96 Ram Samudrala
9/5/96 James Foster
9/5/96 Ram Samudrala
9/6/96 James Foster
8/27/96 Joan Shields
8/28/96 Steve McGrew
8/29/96 David Beorn
8/30/96 Jerry Learn
8/31/96 Doug Easton
8/30/96 Larry Edwards
8/30/96 Doug Yanega
9/7/96 David Beorn
8/27/96 David Dixon
8/28/96 Dana Gourley
8/30/96 Herman Helmuth
9/6/96 Jerry Clark
8/22/96 Truett L Smith
8/28/96 Brian Williams
8/23/96 Karl
8/24/96 Steve McGrew
8/25/96 Arthur Chandler
8/21/96 vorsterd@iafrica.com
8/22/96 Anthony Campbell
8/22/96 Mary K. Kuhner
8/31/96 Arthur Chandler
9/4/96 David Wilson
9/6/96 Ram Samudrala
9/8/96 David Wilson