> NOVA tonight showed another episode of Neanderthal > research.
And, of course, you believe comments about Neanderthal belong in a Mathematics website, right?
A lot of > good new information, but overall it was a > disappointing update > because of the total lack of discussion of the > central and key gene > involved-- HACNS1. > > What do you call it in mathematics, or logic or > science when you > should talk about the key issue, but never talk about > the key issue? > Is it irresponsible? Is it illogical? Is it being a > incompetent > scientist? >
Moot point: you're neither a scientist, nor responsible, and your ability to think clearly is, well... embarrassing.
Of course, you're the only one who's unaware of that. And that is part of the sad story of your life.
> book > (snipped) > > Newsgroups: sci.math, sci.physics > From: Archimedes Plutonium > <plutonium.archime...@gmail.com> > Date: Wed, 9 Mar 2011 13:29:32 -0800 (PST) > Local: Wed, Mar 9 2011 3:29 pm > Subject: Physics and Math completes the science of > Anthropology with > its HACNS1 ; book #184 Rockthrowing theory (sic) > Reply | Reply to author | Forward | Print | > Individual message | Show > original | Remove | Report this message | Find > messages by this author > Newsgroups: sci.anthropology.paleo, sci.anthropology, > sci.math, > sci.physics > From: Archimedes Plutonium > <plutonium.archime...@gmail.com> > Date: Mon, 7 Mar 2011 13:24:33 -0800 (PST) > Local: Mon, Mar 7 2011 3:24 pm > Subject: Homo sapiens has 16-13 = 3 mutations on > HACNS1 that > Neanderthal does not have #183 Rockthrowing theory > book > Reply | Reply to author | Forward | Print | > Individual message | Show > original | Remove | Report this message | Find > messages by this > author > Now my math and physics counting abilities offers me > the fact that 16 > subtract 13 is 3, for ?3 mutations or alterations. > Now maybe Messr > Noonan and Paabo have ?some ?different sort ?of > mathematics when they > are doing anthropology? ?Last time I spoke on this > subject was 2010, > Aug 4, 1:27 am to this ?book of Rockthrowing ?as the > central theory > for evolving the human ?species out of the ape > ?ancestors. I spoke of > how the science of ?Anthropology was a science in > closure or the last > phases of finding ?out ?its history, where the main > parts are solved > and only details ?remain ?to tell the story. The main > parts being, of > course that some 8 ?to 10 ?million years ago some ape > had a > proclivity ?of picking up ?rocks and throwing them > for his advantage. > Advantage in ?gaining more ?food and mates and thus > more children who > had the same ?proclivity of ?throwing stones and > rocks. ?As these > rockthrowers increased in numbers ?there genetic > mutations ?favoring > even better ?abilities of throwing ?caused them to > become bipedal and > more focused ?on even better ?throwing. ?In the end, > these > rockthrowers extincted all other human ?type species > ?such as the > Neanderthals who although were able to ?throw, just > failed ?to have > enough throwing abilities ?of Cro Magnon ?that would > become Homo > sapiens. Neanderthal genetics ?were inferior to ?the > ?throwing > genetics of CroMagnon. ?It was a long time in coming > for ?the > Neanderthal Genome was reported: ?--- quoting from > http://genome.cshlp.org/content/20/5/547.full > ?Neanderthal genomics > and the evolution of modern humans ?James P. Noonan > ?(B) Value of > Neanderthal genome sequence for dating functionally > ?relevant human- > specific substitutions, using the HACNS1 enhancer as > ?an ?example. > (Top) HACNS1 is located in an intron of AGAP1 and > downstream ?of GBX2 > on human chromosome 2. (Bottom) The 13 human-specific > ?substitutions > implicated in the human-specific gain of function in > ?this element. > --- end quoting of Noonan --- ?Now maybe I am not > understanding the > report, but from what I gather ?from these reports > ?of 16 mutations > of ?Homo sapiens compared to only 13 mutations on > ?Neanderthal for > the ?HACNS1: ? 1. Comment on > "Human-Specific Gain of > Function ?in a ?Developmental ...by L Duret - 2009 - > Cited by 13 - > Related ?articles ? 2. Feb 6, 2009 ... > Second, among the > 16 ?substitutions in ?HACNS1 there ?are 14 AT ? GC > substitutions , 2 > GC ? ?CG substitutions, but not a ?single GC ? AT ... > ? 3. > www.sciencemag.org/lookup/resid/323/5915/714c?view=fu > ll&uritype... > ? 4. Human-Specific Gain of Function in a > Developmental > Enhancer ...by ?S Prabhakar - 2008 - Cited by 52 - > Related articles > ? 5. Sep 5, 2008 ... Although the 16 > human-specific > substitutions ?within the 546 ... ? 6. > www.sciencemag.org/ > ?content/321/5894/1346.full??Show ?more results > from sciencemag.org ? ? 7. > HACNS1Human-specific gain of > function in the HACNS1 ?enhancer ... ?it has > experienced 16 human- > specific nucleotide changes ?in the ~6 ?million years > since humans > and ... The cluster of 13 human- ?specific > ?substitutions in 81 bp is > also indicated. ... ? 8. ? > www.yale.edu/noonanlab/ > Noonan_Lab/HACNS1.html - Cached ?- Similar ? > 9. [PDF] DOI: > 10.1126/science.1165848 , 714c (2009); 323 ?Science > et ?al ...File > Format: PDF/Adobe Acrobat - Quick View ? ?10. > by L Duret - > 2009 - Cited by 13 - Related articles ? ?11. > Feb 6, > 2009 ... Second, among the 16 substitutions in > ?HACNS1 ?there are 14 > AT ? GC substitu- tions, 2 GC ? CG substitutions, but > ?not ?a > sin- ... ? 12. > pbil.univ-lyon1.fr/members/duret/.../ ?PDF/ > 2009- ?DuretGaltier.Science.pdf ? 13. > Brief ?communication: > Population data support the ?adaptive ?nature ...by T > ?Hünemeier - > Related articles ? 14. Aug 17, 2010 ... > ?Thirteen of these > 16 mutations are ?found within ?an 81-bp ?functional > .... 2010) shows > that 8 of the 13 human specific ?HACNS1 > ?substitutions ... ? > 15. onlinelibrary.wiley.com ? ... ? ?Journal Home > ? Vol 143 ?Issue > 3 ? ?Abstract ?--- end quoting Google ?hits talking > about 16 > mutations, whereas ?Neanderthal had only ?13 > ?mutations --- ?The > conclusion I draw, which maybe wrong, and someone > ?should correct ?me > if wrong, is that ?Homo sapiens had 16 total > ?alterations in the > HACNS1 gene whereas ?Neanderthal had only ?13 > ?alterations, meaning > that Neanderthal was a different species than ?Homo > sapiens because of > those 3 alterations, but that the alterations > ?missing in Neanderthal > implies CroMagnon was superior in Throwing ?whether > throwing rocks or > stones or spears. And that ?superiority of ?throwing > is the likely > cause of extinction of ?Neanderthal. ?It is ?likely > that the last > places on Earth for Neanderthal were the ?caves ?in > Spain of high > ground, so the higher ground could have ?sheltered > ?them longer from > the superior throwing ?of the encroaching CroMagnon. > ?To throw down > from higher ground tends ?to equalize a superior > ?throwing opponent. > Now I think that Mr. Paabo and Mr. Noonan should > ?have made more > fanfare over the differences of the Neanderthal > ?(Neandertal) HACNS1 > variation and spoken out more on that ?difference. > Perhaps they were > silent about HACNS1 because they seemed ?to have > favored ?the FOXP2 > gene which deals with speech and language. ?So why > the silence over > the fact that Neanderthal had 3 mutations ?different > from CroMagnon > with the HACNS1 gene? Why the silence in the > ?Anthropology community? > One would think ?they should by happy and ?dancing > and celebrating > that their science ?is ?nearly closed and the ?first > major science to > be closed. I guess some ?people just do not ?like to > close their > science. > > -- > Google's archives are top-heavy in hate-spew from > search-engine- > bombing. Only Drexel's Math Forum has done a > excellent, simple and > fair archiving of AP posts for the past 15 years as > seen here: > > http://mathforum.org/kb/profile.jspa?userID=499986 > > Archimedes Plutonium > http://www.iw.net/~a_plutonium > whole entire Universe is just one big atom > where dots of the electron-dot-cloud are galaxies >