Date: Oct 9, 2012 9:43 PM
Author: kirby urner
Subject: Re: Calculus Position Statement - NCTM & MAA
> How lovely for them. Here is what a responsible voice sounds like,
> - ------------------------------
> Description of current changes to the Crestor label
> In a pharmacokinetic study involving a diverse population of Asians residing in the United States, rosuvastatin drug levels were found to be elevated approximately 2-fold compared with a Caucasian control group. As a result of these findings, the "Dosage and Administration" section of the label now states that the 5 mg dose of Crestor should be considered as the start dose for Asian patients and any increase in dose should take into consideration the increased drug exposure in this patient population. Results of this pharmacokinetic study are further discussed under the "Clinical Pharmacology" and "Precautions" section of labeling.
> - -------------------------------
Interesting you'd bring up pharmaceuticals, aka drugs.
BiDil was discussed quite a bit during the presentation.
It's a heart med marketed to blacks, yet it's simply a mixture of two
other heart meds already known to be effective in the general
population. The decision to aim for "African Americans" was a
branding decision. Cigarettes, beers, other products get pitched to
ethniciities for the same reason.
http://www.nitromed.com/ (BiDil ad)
NitroMed gave the NAACP $1.5 million and soon this lobby group was
pushing hard to get Bidil approved by the FDA.
The ?black? label was crucial, because BiDil?s patent covering use in
all ethnic groups expired in 2007, but the patent for blacks only
allows NitroMed to profit from it until 2020. BiDil is a case study in
research methodology ?flaws? that mask strategies calculated to make a
dodgy drug look good on paper, for profit.
> You may know that Crestor is an important drug in the statins class, used to
> ...treat high cholesterol and related conditions, and to prevent cardiovascular disease.
> Crestor is certainly too important to ignore, but it turns out that doctors must take special care with their Asian patients.
> I guess when you study moths, you are free to pretend there are no important differences among human populations. Thank God nobody's life is in their hands.
There are of course genetic sequences in your average Asian that are
higher than in your average non-Asian.
White people are more likely to benefit from sun tan lotion, I buy
that (and the lotion).
What is Asian exactly? Do the people who study genetic patterns
really use such awkward broad brush stroke categories?
Some people in Papua New Guinea are classed as Negroid (named
Negritos) but are genetically far from Africans but for skin color,
are close to neighboring Asians. How would these black Asian people
respond to Crestor? To BiDil? We'll likely never know as you need
fancy insurance to get either and there's no marketing angle here.
As Dr. Chris Smith said last night, using race to make medical
decisions is a bad idea because of all the false negatives and false
positives. If you're concerned about a specific genetic marker, test
for it, don't just assume it will be there base on "race".
Who is more likely to have sickle cell anemia, your average Greek or
your average South African? Answer: average Greek (from the OMSI pub
Per Dr. Drew, it's pretty obvious that the "race" meme was largely
fabricated by white ancestors with an economic stake in having a
racist society like the USA's. Science and religion are both tools of
the trade, when it comes to propagating racism. Both are used to
justify prevailing inequalities.
> No representation without taxation.