Look in the Documentation Center at LinearModelFit. It does exactly what you want.
On Jun 7, 2012, at 2:18 AM, Nicholas Kormanik wrote:
> > I have two columns of data containing predictor variables, and a third which is the response variable. > > All three columns are continuous data. Number of rows is around 500. > > Can Mathematica figure out the relationship between the two predictor variables, and the response variable? > > What would be the code for doing so? > > Thanks. > > Nicholas Kormanik >