NOVA tonight showed another episode of Neanderthal research. A lot of good new information, but overall it was a disappointing update because of the total lack of discussion of the central and key gene involved-- HACNS1.
What do you call it in mathematics, or logic or science when you should talk about the key issue, but never talk about the key issue? Is it irresponsible? Is it illogical? Is it being a incompetent scientist?
In this episode, one of the lead researchers, Svante Paabo is seen as more irresponsible rather than a logical scientist, for his constant incessant focus on FOXP2 gene for language, when a better scientist would have said, "drop that gene" and focus on HACNS1 gene as what made humanity and extincted the Neanderthals.
Perhaps the NOVA crew and Paabo realize that rockthrowing extincted the Neanderthals and are trying to soften that horrible and ugly extinction by painting the Neanderthal as having interbred with the Homo sapiens.
There probably was some interbreeding, but the main idea is that the Neanderthals throwing abilities were so inferior to Homo sapiens that Homo neanderthals were extincted by the constant throwing attacks upon them. Some of the Neanderthal women were probably carried away and interbred, but the men, who could not throw as well as the Homo sapiens were all mercilessly stone thrown to death. Maybe we never want to admit our horrible and grisly past even when the facts come in as such. But that is not responsible science. Science must always tell the truth and full truth.
Instead of focusing on the genes of language and speech or the genes of immunology, the HLA immune system genes, it is irresponsible of Svante Paabo to discuss Neanderthal and neglect the HACNS1 gene.
When your ideas turn out to be false in science, you should have at least the grace to indicate where the major difference is between the Neanderthal and the Homo sapiens-- and that difference is in throwing. So forget about the FOXP2 gene and talk about the HACNS1 gene.
I recommend that Paabo never again have a spot in NOVA on Neanderthal and instead interview Noonan as to the latest information on HACNS1 gene.
The last time I wrote on this textbook was March of 2011 and now it is January of 2013. Looks like I need to do a new edition of this book Rockthrowing for it consolidates and unifies the entire science of Anthropology.
Newsgroups: sci.anthropology.paleo, sci.anthropology, sci.math, sci.physics From: Archimedes Plutonium <plutonium.archime...@gmail.com> Date: Mon, 7 Mar 2011 13:24:33 -0800 (PST) Local: Mon, Mar 7 2011 3:24 pm Subject: Homo sapiens has 16-13 = 3 mutations on HACNS1 that Neanderthal does not have #183 Rockthrowing theory book (snipped)
Newsgroups: sci.math, sci.physics From: Archimedes Plutonium <plutonium.archime...@gmail.com> Date: Wed, 9 Mar 2011 13:29:32 -0800 (PST) Local: Wed, Mar 9 2011 3:29 pm Subject: Physics and Math completes the science of Anthropology with its HACNS1 ; book #184 Rockthrowing theory (sic) Reply | Reply to author | Forward | Print | Individual message | Show original | Remove | Report this message | Find messages by this author Newsgroups: sci.anthropology.paleo, sci.anthropology, sci.math, sci.physics From: Archimedes Plutonium <plutonium.archime...@gmail.com> Date: Mon, 7 Mar 2011 13:24:33 -0800 (PST) Local: Mon, Mar 7 2011 3:24 pm Subject: Homo sapiens has 16-13 = 3 mutations on HACNS1 that Neanderthal does not have #183 Rockthrowing theory book Reply | Reply to author | Forward | Print | Individual message | Show original | Remove | Report this message | Find messages by this author Now my math and physics counting abilities offers me the fact that 16 subtract 13 is 3, for ?3 mutations or alterations. Now maybe Messr Noonan and Paabo have ?some ?different sort ?of mathematics when they are doing anthropology? ?Last time I spoke on this subject was 2010, Aug 4, 1:27 am to this ?book of Rockthrowing ?as the central theory for evolving the human ?species out of the ape ?ancestors. I spoke of how the science of ?Anthropology was a science in closure or the last phases of finding ?out ?its history, where the main parts are solved and only details ?remain ?to tell the story. The main parts being, of course that some 8 ?to 10 ?million years ago some ape had a proclivity ?of picking up ?rocks and throwing them for his advantage. Advantage in ?gaining more ?food and mates and thus more children who had the same ?proclivity of ?throwing stones and rocks. ?As these rockthrowers increased in numbers ?there genetic mutations ?favoring even better ?abilities of throwing ?caused them to become bipedal and more focused ?on even better ?throwing. ?In the end, these rockthrowers extincted all other human ?type species ?such as the Neanderthals who although were able to ?throw, just failed ?to have enough throwing abilities ?of Cro Magnon ?that would become Homo sapiens. Neanderthal genetics ?were inferior to ?the ?throwing genetics of CroMagnon. ?It was a long time in coming for ?the Neanderthal Genome was reported: ?--- quoting from http://genome.cshlp.org/content/20/5/547.full ?Neanderthal genomics and the evolution of modern humans ?James P. Noonan ?(B) Value of Neanderthal genome sequence for dating functionally ?relevant human- specific substitutions, using the HACNS1 enhancer as ?an ?example. (Top) HACNS1 is located in an intron of AGAP1 and downstream ?of GBX2 on human chromosome 2. (Bottom) The 13 human-specific ?substitutions implicated in the human-specific gain of function in ?this element. --- end quoting of Noonan --- ?Now maybe I am not understanding the report, but from what I gather ?from these reports ?of 16 mutations of ?Homo sapiens compared to only 13 mutations on ?Neanderthal for the ?HACNS1: ? 1. Comment on "Human-Specific Gain of Function ?in a ?Developmental ...by L Duret - 2009 - Cited by 13 - Related ?articles ? 2. Feb 6, 2009 ... Second, among the 16 ?substitutions in ?HACNS1 there ?are 14 AT ? GC substitutions , 2 GC ? ?CG substitutions, but not a ?single GC ? AT ... ? 3. www.sciencemag.org/lookup/resid/323/5915/714c?view=full&uritype... ? 4. Human-Specific Gain of Function in a Developmental Enhancer ...by ?S Prabhakar - 2008 - Cited by 52 - Related articles ? 5. Sep 5, 2008 ... Although the 16 human-specific substitutions ?within the 546 ... ? 6. www.sciencemag.org/ ?content/321/5894/1346.full??Show ?more results from sciencemag.org ? ? 7. HACNS1Human-specific gain of function in the HACNS1 ?enhancer ... ?it has experienced 16 human- specific nucleotide changes ?in the ~6 ?million years since humans and ... The cluster of 13 human- ?specific ?substitutions in 81 bp is also indicated. ... ? 8. ? www.yale.edu/noonanlab/ Noonan_Lab/HACNS1.html - Cached ?- Similar ? 9. [PDF] DOI: 10.1126/science.1165848 , 714c (2009); 323 ?Science et ?al ...File Format: PDF/Adobe Acrobat - Quick View ? ?10. by L Duret - 2009 - Cited by 13 - Related articles ? ?11. Feb 6, 2009 ... Second, among the 16 substitutions in ?HACNS1 ?there are 14 AT ? GC substitu- tions, 2 GC ? CG substitutions, but ?not ?a sin- ... ? 12. pbil.univ-lyon1.fr/members/duret/.../ ?PDF/ 2009- ?DuretGaltier.Science.pdf ? 13. Brief ?communication: Population data support the ?adaptive ?nature ...by T ?Hünemeier - Related articles ? 14. Aug 17, 2010 ... ?Thirteen of these 16 mutations are ?found within ?an 81-bp ?functional .... 2010) shows that 8 of the 13 human specific ?HACNS1 ?substitutions ... ? 15. onlinelibrary.wiley.com ? ... ? ?Journal Home ? Vol 143 ?Issue 3 ? ?Abstract ?--- end quoting Google ?hits talking about 16 mutations, whereas ?Neanderthal had only ?13 ?mutations --- ?The conclusion I draw, which maybe wrong, and someone ?should correct ?me if wrong, is that ?Homo sapiens had 16 total ?alterations in the HACNS1 gene whereas ?Neanderthal had only ?13 ?alterations, meaning that Neanderthal was a different species than ?Homo sapiens because of those 3 alterations, but that the alterations ?missing in Neanderthal implies CroMagnon was superior in Throwing ?whether throwing rocks or stones or spears. And that ?superiority of ?throwing is the likely cause of extinction of ?Neanderthal. ?It is ?likely that the last places on Earth for Neanderthal were the ?caves ?in Spain of high ground, so the higher ground could have ?sheltered ?them longer from the superior throwing ?of the encroaching CroMagnon. ?To throw down from higher ground tends ?to equalize a superior ?throwing opponent. Now I think that Mr. Paabo and Mr. Noonan should ?have made more fanfare over the differences of the Neanderthal ?(Neandertal) HACNS1 variation and spoken out more on that ?difference. Perhaps they were silent about HACNS1 because they seemed ?to have favored ?the FOXP2 gene which deals with speech and language. ?So why the silence over the fact that Neanderthal had 3 mutations ?different from CroMagnon with the HACNS1 gene? Why the silence in the ?Anthropology community? One would think ?they should by happy and ?dancing and celebrating that their science ?is ?nearly closed and the ?first major science to be closed. I guess some ?people just do not ?like to close their science.
-- Google's archives are top-heavy in hate-spew from search-engine- bombing. Only Drexel's Math Forum has done a excellent, simple and fair archiving of AP posts for the past 15 years as seen here: