Simulations Nab Protein-folding Mistakes
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|Ivars Peterson - Science News Online|
|The human body manufactures thousands of different proteins, which act as enzymes, structural elements, or carriers. Each protein starts out as a long strand that must fold itself into the proper shape to perform its specific function. To gain insights into the folding process, researchers have developed mathematical models that attempt to capture how a single strand rapidly collapses into its correct configuration. New computer simulations now reveal how one protein strand can interfere with the folding of another... The results could help laboratory scientists understand the mechanisms underlying protein-folding mistakes, which are implicated in Alzheimer's disease and other maladies.|
|Levels:||High School (9-12), College|
|Math Topics:||Medicine/Health, Human Biology, Computer Science|
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